姓名：阳乐涛

导师情况：博士生导师

研究领域：生物材料

研究方向：

1. 靶向药物递送

2. 细胞生物力学

3. 神经组织工程

Email: yangletao@tongji.edu.cn

通讯地址：上海市杨浦区四平路1239号，天游线路检测中心，邮编200092

个人简介

阳乐涛，博士，天游线路检测中心教授，天游线路检测中心附属同济医院柔性引进人才，脊柱脊髓损伤再生修复教育部重点实验室PI。本科和博士先后毕业于南开大学化学学院、美国罗格斯大学化学生物学系，并于2022年在美国哥伦比亚大学生物医学工程系完成博士后训练，随后加入天游线路检测中心。近年来在Advanced Materials、Science Advances、National Science Reviews、Research、Advanced Functional Materials、ACS Nano、Nano Letters、Biomaterials等中科院一区期刊以通讯及第一/共一作者发表高水平文章>15篇，共发表文章>50篇，总引用数2300余次，H-index为22。担任中国研究型医院学会神经再生与修复专委会常务委员、Exploration、BMEMat、《中国组织工程研究》及Advanced Technology in Neuroscience等知名期刊学术编辑或青年编委。曾获得Rutgers TechAdvance Award、Columbia TRx Award和国际神经再生修复学会青年论坛一等奖，并于2022年获批上海市海外高层次青年人才和国家海外高层次青年人才。

 近五年一区Top期刊发表论文（*通讯作者，†共同第一作者）：  

1. Hou Y, Conklin B, Choi HK, Yang L*, KiBum Lee*. Probing Nanotopography-mediated Macrophage Polarization via Integrated Machine Learning and Combinatorial Biophysical Cue Mapping. 2024, Accepted, DOI: https://doi.org/10.1021/acsnano.4c04406.

2. Yang L, Rathnam C, Hou Y, Patel M, Cai L, Lee K. Rapid and Controllable Multilayer Cell Sheet Assembly via Biodegradable Nanochannel Membranes. 2024, 2403367, DOI: https://doi.org/10.1002/adfm.202403367

3. Yang L*, Rathnam C, Hidaka T, Hou Y, Conklin B, Pandian GN, Sugiyama H, Lee KB. A Nanoparticle-based Artificial Mitochondrial DNA (mtDNA) Transcription Regulator: MitoScript. Nano Letters. 2023 (accepted), DOI: 10.1021/acs.nanolett.2c03958

4. Conley BM†, Yang L†, Basanta B, Luo J, Han I, Lee KB. Development of a Nano-Hybrid Peptide Hydrogel for Enhanced Intervertebral Disc Repair and Regeneration. ACS Nano. 2023 (accepted), DOI: 10.1021/acsnano.2c11441

5. Yang L, Lin YH, Zhu Y, Ding S, Margolis KG, Leong KW. Material Engineering in Gut Microbiome and Human Health. Research. 2022, 9804014.

6. Yang L, Conley B, Rathnam C, Cho HY, Lee JH, Lee KB. A Predictive Biophysical Cue Mapping Approach for Cellular Reprogramming Using Combinatorial Nanoarrays. ACS Nano. 2022, 16, 4, 5577–5586.

7. Wang S†, Yang L.† et al. Injectable Hybrid Inorganic Nanoscaffold-templated Rapid Stem Cell Assembly for Accelerated Cartilage Repair. National Science Review. 2022, 9, nwac037.

8. Yang L, Conley B, Rathnam C, Pongkulapa T, Conklin B, Hou Y, Lee K.-B. High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and Machine Learning Approach. Research. 2022, 9784273.

9. Yang L, Patel KD, Rathnam C, Thangam R, Hou Y, Kang H, Lee KB. Harnessing the Therapeutic Potential of Extracellular Vesicles for Biomedical Applications Using Multifunctional Magnetic Nanomaterials. Small. 2022, 18, 2104783.

10. Rathnam C.†, Yang L†, Castro-Pedrido S, Cai L, Lee K.-B. Hybrid SMART Spheroids for Enhanced Stem Cell-based Treatment of CNS Injuries. Science Advances. 2021, 7, 40.

11. Yang L†, Conley B†, Cerqueira RS†, Pongkulapa T, Wang S, Lee JK, Lee KB. Effective Modulation of CNS Inhibitory Microenvironment using Bio-inspired Hybrid Nanoscaffold-based Therapeutic Interventions. Advanced Materials. 2020, 202002578.

12. Yang L, Kim TH, Cho HY, Chueng STD, Lee JM, Luo J, Yin PT, Han J, Kim JH, Chung BG, Choi JW, Lee, KB. Hybrid Graphene Oxide/Gold Nanoparticle-based Nucleic Acid Conjugates for Cancer-Specific Multimodal Imaging and Combined Therapeutics. Advanced Functional Materials. 2020, 31, 2006918. 

13. Wang S.-Q.†, Yang L†, Cho H.-Y, Chueng S.-T.-D, Zhang H.-P, Zhang Q.-Y, Lee K.-B. Developing Redox and Light Responsive Core-shell Nanoparticle for Photo-Chemical Enhanced Chemodynamic Therapy. Biomaterials. 2019, 224, 119498.

14. Yang L†, Lee J.-H.†, Rathnam C, Hou Y.-N, Choi J.-W, Lee K.-B. Dual-Enhanced Raman Scattering-based Characterization of Stem Cell Differentiation using Graphene-Plasmonic Hybrid Nanoarray. Nano Letters. 2019, 11, 8138-8148.

15. Yang L, Chueng STD, Li Y, Patel M, Rathnam C, Dey G, Wang L, Cai L, Lee KB. A Biodegradable Hybrid Inorganic Nanoscaffold for Advanced Stem Cell Therapy. Nature Communications. 2018, 9, 3147.8.